News for Healthier Living

AI-Powered Atlas Reveals New Insights Into Tertiary Lymphoid Structures as Prognostic and Response Biomarkers in Cancer

New spatial atlas of immune cell structures, called tertiary lymphoid structures (TLSs), reveals how key features vary across tumor types and influence patient outcomes New spatial atlas of immune cell structures, called tertiary lymphoid structures (TLSs), reveals how key features vary across tumor types and influence patient outcomes Researchers developed scalable AI frameworks to detect, profile and classify these structures from spatial multi-omics data and routine pathology slides Researchers developed scalable AI frameworks to detect, profile and classify these structures from spatial multi-omics data and routine pathology slides Composite scoring approach outperformed conventional TLS measures in stratifying patients by prognosis and treatment response Composite scoring approach outperformed conventional TLS measures in stratifying patients by prognosis and treatment response Atlas represents a significant step forward in understanding TLS biology and advancing TLS-based biomark

May 28, 2026


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