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News for Healthier Living
Enantioselective Maternal Transfer of Pesticide Metabolite and Its Thyroid Effects
 Estimating the multigenerational effects of chiral pesticide metabolites is essential for fully understanding their ecological impacts. This study demonstrated that S-o,p'-DDD accumulated preferentially in adult zebrafish and transferred more efficiently to their offspring compared to the R-enantiomer, leading to pronounced developmental defects and endocrine disruption across both generations. Molecular docking against key thyroid-related proteins provided a mechanistic explanation for this stereospecific toxicity. These findings suggest that evaluating only racemic mixtures may underestimate real-world hazards.
November 26, 2025
December 1 2025November 30 2025November 29 2025November 28 2025November 27 2025November 26 2025November 25 2025November 24 2025November 23 2025November 22 2025November 21 2025November 20 2025November 19 2025November 18 2025 - Parental Monitoring Is Linked to Fewer Teen Conduct Problems Despite Genetic Risk
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